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However, when standing in front of a patient in a clinical setting, some argue that it is deceiving for a DNP to introduce themselves as doctor, even unacceptable if they passively allow patients to use the title.

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We are advancing five simple principles: drug manufacturers claiming a value proposition should provide documentation to justify such claims; drug manufacturers should make postlaunch price increases more predictable to help patients and the overall health system budget for future costs; drug manufacturers launching new products should disclose likely populations, the launch price and any value proposition immediately upon FDA approval; drug manufacturers should make available all clinical data to help third party researchers evaluate comparative effectiveness and value; and drug manufacturer participation in organisations that influence coverage decisions should be transparent and free from conflicts of interest.

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Search date 2004; the Cochrane Central Register of Controlled Trials (CENTRAL), NHS Health Economics Database, Medline, Embase, Current Controlled Trials, National Research Register, hand searches of reference lists of relevant trials and reviews, and contact with experts.

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